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Discovery increases knowledge about the immune system

For the first time ever, researchers have succeeded in measuring the interaction between the CD4 molecule and molecule complex MHC class II, and how they bind to each other can determine whether an immune response in the body is launched or not. The measured strength of this interaction increases the understanding of what happens during the initial phase when the body’s immune system is switched on.
Illustration: Peter Jönsson
Illustration: Peter Jönsson

So far the research is basic, but in the future, the discovery can contribute to increased knowledge about the failure of our immune system to respond to various so-called autoimmune diseases, i.e. diseases caused by the human immune system attacking its own body.

“Our results may become valuable in the future when developing new drugs and for making diagnosis”, says Peter Jönsson, physical chemist at the Lund University Faculty of Science.

The study was conducted in laboratories with researchers in Oxford and Cambridge.

The article is published in the scientific journal PNAS.

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