In Swedish
| Title | Clinical dosimetry in the treatment of bone tumors: old and new agents |
| Author/s | Cecilia Hindorf, G. D. Flux, C. Ibisch, F. Kraeber Bodere |
| Department/s |
Radiation Physics, Lund
|
| Full-text | Full text is not available in this archive |
| Publication/Series | Quarterly Journal Of Nuclear Medicine And Molecular Imaging |
| Publishing year | 2011 |
| Volume | 55 |
| Issue | 2 |
| Pages | 198 - 204 |
| Document type | Journal article |
| Status | published |
| Quality controlled | yes |
| Language | English |
| Publisher | Edizioni Minerva Medica |
| Abstract English | Treatment of multisite, sclerotic bone metastases is successfully performed by radionuclide therapy. Pain palliation is the most common aim for the treatment. Two radiopharmaceuticals are currently approved by the European Medicines Agency (Sm-153-EDTMP and Sr-89-Cl-2) whilst other radiopharmaceuticals are at different stages of development, or are approved in some European countries (Re-186-HEDP, Sn-117(m)-DTPA and Ra-223-Cl-2). The tissues at risk for the treatment are bone marrow and normal bone. A review of the methods applied for dosimetry for these tissues and for tumours is performed, including the calculation of S values (the absorbed dose per decay) and optimal procedures on how to obtain biodistribution data for each radiopharmaceutical. The dosimetry data can be used to individualise and further improve the treatment for each patient. Dosimetry for radionuclide therapy of bone metastases is feasible and can be performed in a routine clinical practice. |
| Subject |
Medicine and Health Sciences |
| Keywords | Radionuclide therapy, Radiotherapy planning, Neoplasm metastasis, computer-assisted |
| ISBN/ISSN/Other |
ISSN: 1824-4661 |
Last modified 19 Apr 2013
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